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Date Published: 08/10/2025
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DOI: https://doi.org/10.51298/vmj.v554i3.15797
Issue
Vol. 554 No. 3 (2025)
Section
Các bài báo
How to Cite
Lâm, T. Q. M., & Trần, X. V. (2025). MINERALIZATION POTENTIAL OF CALCIUM SILICATE-BASED ROOT CANAL SEALERS ON HUMAN PERIODONTAL LIGAMENT STEM CELLS. Vietnam Medical Journal, 554(3). https://doi.org/10.51298/vmj.v554i3.15797

MINERALIZATION POTENTIAL OF CALCIUM SILICATE-BASED ROOT CANAL SEALERS ON HUMAN PERIODONTAL LIGAMENT STEM CELLS

Thị Quỳnh Mai Lâm, Xuân Vĩnh Trần

Main Article Content

Abstract

Objective: This study evaluates the mineralization potential of two calcium silicate-based root canal sealers: BioRoot™ RCS (Septodont, Saint-Maur-des-Fossés, France) and CeraSeal (Meta-Biomed, Korea). Methods: Human periodontal ligament stem cells (hPDLSCs) were directly exposed to the 25% extract concentration of each sealer (a concentration considered safe in cytotoxicity studies). Mineralization potential was assessed using the Alizarin Red staining assay. Results: There was no significant difference in the mineralization potential between the two types of sealers and the control group (p > 0.05). Conclusion: Calcium silicate-based root canal sealers exhibit mineralization-stimulating activity on cells.

Article Details

Keywords

Mineralization, calcium silicate- root canal sealer, BioRootTM RCS, CeraSeal, human periodontal ligament stem cells.

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