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Date Published: 08/10/2025
Abstract Views: 235
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DOI: https://doi.org/10.51298/vmj.v554i3.15809
Issue
Vol. 554 No. 3 (2025)
Section
Các bài báo
How to Cite
Trịnh , V. C., & Đào, V. H. (2025). EVALUATION OF TRANSIENT LOWER ESOPHAGEAL SPHINCTER RELAXATIONS IN PATIENTS WITH GASTROESOPHAGEAL REFLUX DISEASE. Vietnam Medical Journal, 554(3). https://doi.org/10.51298/vmj.v554i3.15809

EVALUATION OF TRANSIENT LOWER ESOPHAGEAL SPHINCTER RELAXATIONS IN PATIENTS WITH GASTROESOPHAGEAL REFLUX DISEASE

Văn Cương Trịnh , Việt Hằng Đào

Main Article Content

Abstract

Objectives: The aims of this study were to investigate the prevalence and characteristics of transient lower esophageal sphincter relaxation (TLESR) in patients with gastroesophageal reflux disease (GERD) symptoms using high-resolution manometry (HRM); and to assess the association between TLESR with clinical characteristics and endoscopic findings. Methods: A descriptive study was conducted among 100 patients with gastroesophageal reflux symptoms performed HRM from March 2025 to June 2025 at the Institute of Gastroenterology and Hepatology and Hoang Long Clinic. Results: TLESR was identified in 44 out of 100 patients (44%), with a total of 74 events recorded. The mean duration of TLESR events was 20.1 ± 5.4 seconds. The rate of TLESR associated with reflux episodes was 60.8%. While TLESRs were more significantly frequent in females, the prevalence of reflux esophagitis on endoscopy was higher in males (OR=2.81, p<0.05). Patients having TLESR had significantly higher prevalence of belching and regurgitation compared to those without TLESR. There were no significant differences in endoscopic findings, HRM results (LES pressure, IRP 4, and esophageal motility disorders) between 2 groups.

Article Details

Keywords

Gastroesophageal reflux disease, HRM, Transient Lower Esophageal Sphincter Relaxations (TLESR).

References

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