COMPLICATION AFTER HEPATECTOMY FOR HEPATOCELLULAR CARCINOMA

Văn Linh Hồ, Quốc Ái Đặng

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Abstract

Objective: Describe the incidence and contributing factors associated with postoperative complications following hepatectomy for liver cancer. Materials and Methods: From January 2017 to May 2025, a total 406 patients underwent liver resection for hepatocellular carcinoma in Hue Central Hospital. Results: Among 406 patients who underwent liver resection with results were obtained: The mean age was 61 ± 11,9 (30-80) years, the male/female ratio was approximately 4:1. Major liver resections accounted for 52,5%, while minor resections accounted for 47,5%. The mean time intermitent Pringle manoeuvre was 42,5 ± 17,3 (15-90) minutes. Postoperative complications were recorded in 50 patients (12.3%), with a total of 71 complications observed. The most common complication is suppuration of the surgical wound (4,2%), biliary fistulas 3,2%, intra-abdominal abscess 2,7%, pleural effusion 1,7%, liver failure 2,2%, persistent ascites 2,2% and less comment intra-abdominal bleeding 0,7%. Mortality rate was 0.7% cases. Conclusion: Major liver resection is associated with postoperative liver failure, it is a potentially lethal complication with few therapeutic options. Patient selection and preoperative care are crucial for its prevention. The overall rate of postoperative complications following liver resection remains high, with surgical site infections being the most common, followed by bile leakage. Although these complications are not usually life-threatening, but they can significantly prolong the hospital stay time.

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References

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