TỈ SỐ TIỂU CẦU - LYMPHO BÀO TRONG DỰ ĐOÁN BIẾN CỐ TIM MẠCH NỘI VIỆN Ở NGƯỜI NHỒI MÁU CƠ TIM CẤP

Abstract

Background: Although prognostic scoring systems and cardiac biomarkers have significantly aided in the management of AMI patients, in-hospital mortality and complications remain prevalent, particularly in lower-level healthcare facilities with limited access to equipment and laboratory testing. Therefore, there is a growing need for simple, practical, and effective prognostic tools that can be readily applied in clinical practice. Objective: To investigate the association between the platelet-to-lymphocyte ratio (PLR) and certain clinical characteristics AMI, to evaluate its prognostic value in predicting in-hospital cardiovascular events in patients with AMI. Subjects and research methods: A retrospective analysis was conducted on 112 patients admitted to the Interventional Cardiology Department of University Medical Center Ho Chi Minh City, Campus 1, from January 2023 to January 2025. Results: There were 112 patients enrolled in the study, a PLR >152.91 was significantly associated with longer hospital stays and a higher incidence of in-hospital cardiovascular events—7.667 times higher compared to patients with a PLR ≤152.91. Receiver operating characteristic (ROC) curve analysis showed an area under the curve (AUC) for PLR of 0.749 (95%CI: 0.658–0.826), Killip classification AUC of 0.839 (95%CI: 0.758–0.902), GRACE score AUC of 0.846 (95%CI: 0.766–0.908), and NLR AUC of 0.808 (95%CI: 0.723–0.877). The differences between these AUCs were not statistically significant (p>0.05) in predicting in-hospital adverse cardiovascular events in AMI patients. Conclusion: PLR is a reasonable marker for predicting in-hospital cardiovascular events in patients with AMI and may be considered for use in primary care and lower-level healthcare settings