COMPARISON OF THE PROGNOSTIC VALUE OF MAP(ASH) SCORE AND MELD SCORE IN CIRRHOTIC PATIENTS WITH GASTROINTESTINAL BLEEDING DUE TO RUPTURED ESOPHAGEAL VARICES
Main Article Content
Abstract
Objective: Comparison of the prognostic value of 90-day mortality and rebleeding using the MAP(ASH) score and MELD index in cirrhotic patients with gastrointestinal bleeding (GIB) due to esophageal variceal rupture. Methods: A descriptive, prospective study was conducted on 114 cirrhotic patients with GIB caused by esophageal variceal rupture at the Gastroenterology and Hepatology Center, Bach Mai Hospital, from October 2024 to May 2025. MAP(ASH) and MELD scores were assessed within the first 24 hours of admission. Patients were monitored for rebleeding and mortality over 90 days. Results: Both MAP(ASH) and MELD showed good predictive value for mortality, with areas under the ROC curve (AUROC) of 0.842 (95% CI: 0.686 – 0.998; p < 0,001) and 0.869 (95% CI: 0.724 – 1.00; p < 0.001), respectively. For rebleeding, MAP(ASH) and MELD demonstrated fair predictive value, with AUROCs of 0.731 (95% CI: 0.612 – 0.850) and 0.712 (95% CI: 0.589 - 0.835), respectively, both statistically significant (p < 0.001). Conclusion: Both MAP(ASH) and MELD scores have good prognostic value for 90-day mortality and rebleeding in cirrhotic patients with GIB due to esophageal varices. Among them, the MELD score was more valuable in predicting mortality, while the MAP(ASH) score was more useful in predicting rebleeding.
Article Details
Keywords
MAP(ASH) score, MELD, cirrhosis, esophageal variceal bleeding.
References
2. E. Redondo-Cerezo et al., “MAP(ASH): A new scoring system for the prediction of intervention and mortality in upper gastrointestinal bleeding,” J Gastroenterol Hepatol, vol. 35, no. 1, pp. 82–89, Jan. 2020, doi: 10.1111/jgh.14811.
3. De Franchis, R., Bosch, J., Garcia-Tsao, G., Reiberger, T., Ripoll, C., & Baveno VII Faculty. (2022). Baveno VII - Renewing consensus in portal hypertension. Journal of Hepatology, 76(4), 959–974. https://doi.org/10. 1016/j.jhep.2021.12.022.
4. Huy, D. Q., Chung, N. V., & Dong, D. T. (2023). Value of Some Scoring Systems for the Prognosis of Rebleeding and In-Hospital Mortality in Liver Cirrhosis with Acute Variceal Bleeding. Gastroenterology Insights, 14(2), 144-155. https://doi.org/10.3390/gastroent14020011.
5. Nguyễn THT, Trần T Ánh T, Nguyễn VM, Trần TL, Nguyễn AT, Đinh TG, Nguyễn TH, Mai TH, Mai TB. Nghiên cứu giá trị của thang điểm MAP(ASH) trong tiên lượng chảy máu tiêu hóa do vỡ giãn tĩnh mạch thực quản, tĩnh mạch phình vị ở bệnh nhân xơ gan. VMJ. 2024;539(3). doi:10.51298/vmj.v539i3.10021.
6. Motola-Kuba M., Arzate A.E., (2016), "Validation of prognostic scores for clinical outcomes in cirrhotic patients with acute variceal bleeding", Annasl of Hepatology, 15(6), pp. 895-901.
7. Krishnan A, Woreta TA, Vaidya D, Liu Y, Hamilton JP, Hong K, et al. MELD or MELD-Na as a Predictive Model for Mortality Following Transjugular Intrahepatic Portosystemic Shunt Placement. J Clin Transl Hepatol. 2023;11(1):38-44. doi:10.14218/JCTH.2021.00513.