ĐẶC ĐIỂM DỊCH TỄ HỌC, LÂM SÀNG VÀ DIỄN TIẾN CỦA TAY CHÂN MIỆNG NẶNG TẠI BỆNH VIỆN NHI ĐỒNG THÀNH PHỐ NĂM 2023

Abstract

Background: Hand, foot, and mouth disease (HFMD) is a common pediatric infection. A significant proportion of cases may progress to severe forms with neurological, respiratory, and circulatory complications. This study aimed to describe the epidemiological, clinical characteristics, and disease progression of severe HFMD cases at Children's Hospital of Ho Chi Minh City in 2023. Methods: A retrospective descriptive study was conducted on 811 hospitalized children diagnosed with severe HFMD (grade 2b or higher) from January to December 2023. Data were collected from electronic medical records and analyzed using descriptive statistics. Results: Severe HFMD accounted for 26.6% of total HFMD hospitalizations. Most cases were under 3 years of age (72%) and male (63%). Common neurological signs included myoclonus (44.7%), ataxia/tremors (56.5%), and meningitis (28.2%). Respiratory failure occurred in 19.3%, hypertension in 10.8%, and shock in 1.6%. A total of 273 cases (33.6%) progressed to more severe stages during hospitalization. Endotracheal intubation was performed in 10.5% and continuous renal replacement therapy in 1.85%. Conclusion: Severe HFMD is associated with complex clinical progression and multiorgan involvement. Early recognition and timely management play a critical role in improving patient outcomes.