KẾT QUẢ ĐIỀU TRỊ HẠT CƠM PHẲNG Ở TRẺ EM BẰNG DUNG DỊCH KẼM SULPHATE 10%

Abstract

Objective: To describe the clinical characteristics of flat warts in children and to compare the treatment outcomes of 10% zinc sulphate solution versus 10% salicylic acid ointment in treating flat warts in pediatric patients. Methods: This study was conducted from September 2024 to July 2025 at the National Hospital of Dermatology and Venereology, involving 107 pediatric patients. Of these, 72 patients were randomly assigned to two treatment groups. Results: After 4 weeks, the complete lesion clearance rate in the 10% zinc sulphate group was 36.6%, compared to 12.9% in the 10% salicylic acid group, showing a statistically significant difference (p=0.024). The proportion of patients without adverse effects was significantly higher in the salicylic acid group (87.1%) compared to the zinc sulphate group (34.2%). Redness and itching were observed in 61% of patients in the zinc sulphate group, compared to 12.9% in the salicylic acid group (p < 0.01). Conclusion: Treatment of flat warts in children with 10% zinc sulphate solution shows better outcomes than treatment with 10% salicylic acid ointment. However, some adverse effects such as itching, redness, scaling, and skin erosion may occur with zinc sulphate, though most are mild and self-limiting.