KHẢO SÁT NỒNG ĐỘ PHOSPHO MÁU Ở NGƯỜI BỆNH THẬN NHÂN TẠO CHU KỲ TẠI BỆNH VIỆN BẠCH MAI

Abstract

Background: Disorders of phosphorus metabolism increase the risk of cardiovascular disease and represent a leading cause of mortality in patients with chronic kidney disease. Malnutrition is a common condition among patients undergoing hemodialysis. This study aims to investigate the association between serum phosphorus levels and the nutritional status of patients receiving maintenance hemodialysis. Objectives: To investigate serum phosphorus levels in patients undergoing maintenance hemodialysis and to explore the association between serum phosphorus and various clinical and paraclinical factors in this patient population. Methods: A cross-sectional descriptive study was conducted on 202 patients receiving maintenance hemodialysis at the Nephrology and Dialysis Center, Bach Mai Hospital. Results: The mean serum phosphorus level was 1.66 ± 0.62 mmol/L. The prevalence of hypophosphatemia, normophosphatemia, and hyperphosphatemia was 20.3%, 39.1%, and 40.6%, respectively. The mean calcium-phosphorus product was 3.93 ± 1.59 mmol²/L². Serum phosphorus levels were positively correlated with parathyroid hormone (PTH), serum creatinine, and the calcium-phosphorus product. There was a statistically significant association between serum phosphorus and body mass index (BMI) (p < 0.001), as well as nutritional status. Conclusions: Hypophosphatemia is a common condition among patients on maintenance hemodialysis and is closely associated with malnutrition, as reflected by reduced BMI and serum albumin levels in the study population.