ĐẶC ĐIỂM CẬN LÂM SÀNG CỦA BỆNH NHÂN UNG THƯ ĐẠI TRỰC TRÀNG TẠI BỆNH VIỆN TRUNG ƯƠNG THÁI NGUYÊN

Abstract

Objective: To describe the paraclinical characteristics of patients with colorectal cancer at Thai Nguyen National Hospital. Subjects and Methods: A cross-sectional descriptive study was conducted on 107 patients diagnosed with colorectal adenocarcinoma based on clinical presentation, endoscopy, and histopathological evaluation through endoscopic biopsy. The study population was assessed for metabolic syndrome at Thai Nguyen National Hospital from June 2024 to June 2025. Results: The mean age was 55.83 ± 5.26 years. The rate of unsuccessful endoscopic intubation due to tumor obstruction was 53.3%. The average carcinoembryonic antigen (CEA) level was 55.09 ± 168.34 ng/mL, with 52.3% of patients having a CEA level ≤ 5 ng/mL. The mean tumor size was 36.53 ± 34.14 mm, with 41.1% of tumors measuring less than 20 mm. Histopathologically, adenocarcinoma accounted for the majority (94.4%), with only one case of signet-ring cell carcinoma. Low-grade malignancy was observed in 68.2% of cases, while high-grade malignancy was present in 31.8%. Conclusion: The findings indicate that colorectal cancer predominantly affects middle-aged individuals, with adenocarcinoma being the most common histological subtype and low-grade malignancy prevailing. However, a considerable number of patients presented with large tumors or tumors that impeded endoscopic passage, underscoring the need for enhanced early detection and routine screening efforts.