KHẢO SÁT HÌNH THÁI VÀ CHỨC NĂNG NHĨ TRÁI BẰNG SIÊU ÂM TIM Ở BỆNH NHÂN BỆNH THẬN MẠN TÍNH GIAI ĐOẠN CUỐI TRƯỚC VÀ SAU GHÉP THẬN

Abstract

Objective: To investigate the changes in left atrial morphology and function by echocardiography in patients with end-stage chronic kidney disease before and after kidney transplantation. Subjects and methods: Prospective, descriptive study, including 63 patients diagnosed with end-stage chronic kidney disease and treated with kidney transplantation at Military Hospital 103 from October 2024 to April 2025. Results: The left atrial morphology (LAD, LAVi) decreased significantly after kidney transplantation (LAD: 35.11 ± 6.72 and 30.95 ± 4.83 mm, p < 0.01) (LAVi: 29.09 ± 13.12 and 21.35 ± 7.90 ml/m2, p < 0.01). Left atrial function, including the left atrial reservoir strain (LASr), the left atrial conduit strain (LAScd), and the left atrial contraction strain (LASct) on the 2-chamber and 4-chamber views after kidney transplantation, all improved (p < 0.01). These indices evaluated after transplantation in the conservative treatment group before transplantation were significantly lower than in the hemodialysis group (p < 0.01). LASr in the hemodialysis group under 12 months was lower than in the over 12 months group (45.1 ± 7.1 and 47.2 ± 3.4, p < 0.01). There was no difference between LASr, LAScd, LASct, and the left atrial size with pre-transplant dialysis time (p > 0.05). Conclusion: The left atrial morphology (LAD, LAVi) and the left atrial functions (LASr, LAScd, LASct) after kidney transplantation were significantly reduced compared to pre-transplant. These indices, after transplantation, were related to treatment methods as well as pre-transplant dialysis time