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Date Published: 29/10/2025
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DOI: https://doi.org/10.51298/vmj.v555i1.15931
Issue
Vol. 555 No. 1 (2025)
Section
Các bài báo
How to Cite
Nguyễn, T. T., Lưu, T. B., Nguyễn, T. H., & Nguyễn, T. H. (2025). RESULTS OF TREATMENT OF PATIENTS WITH PRIMARY KNEE OSTEOARTHRITIS WITH ORAL PREPARATION CONTAINING AVOCADO/SOYBEAN UNSAPONIFIABLES (PIASCLEDINE@). Vietnam Medical Journal, 555(1). https://doi.org/10.51298/vmj.v555i1.15931

RESULTS OF TREATMENT OF PATIENTS WITH PRIMARY KNEE OSTEOARTHRITIS WITH ORAL PREPARATION CONTAINING AVOCADO/SOYBEAN UNSAPONIFIABLES (PIASCLEDINE@)

Thị Tuyết Nguyễn, Thị Bình Lưu, Trọng Hiếu Nguyễn, Thị Hiền Nguyễn

Main Article Content

Abstract

Objective: To assess the therapeutic efficacy of Piascledine@ in the management of primary knee osteoarthritis in Thai Nguyen province. Subjects and methods: This was a cross-sectional descriptive study conducted on 100 patients (158 knees) with confirmed diagnoses of primary knee osteoarthritis, treated with Piascledine@ 300 mg at the Department of Rheumatology, Thai Nguyen A Hospital. All participants met the inclusion criteria and were enrolled between July 1, 2024 and May 1, 2025. Results: Pain symptoms of patients in the study improved significantly, the average VAS score VAS T0 5.5 ± 1.9; T6 2.0 ± 1.9 (p < 0.05); WOMAC pain score T0 12.3 ± 0.9; T6 2.1 ± 0.9 (p < 0.05); WOMAC stiffness score T0 4.1 ± 1.6; T6 1.0 ± 0.7 (p < 0.05); WOMAC movement score T0 30.7 ± 7.9; T6 12.5 ± 7.9 (p < 0.05). The proportion of knees with good and satisfactory treatment outcomes was 28.5% and 69.6%, respectively. Adverse effects were minimal, including headache (4.0%) and epigastric pain (1.0%), with no cases requiring treatment discontinuation. The mean patient satisfaction score was 8.8 ± 1.2 points; 92.0% of patients reported being very satisfied, and 6.0% were satisfied. Conclusion: Taking Piascledine@ is safe and clearly effective in improving symptoms of knee osteoarthritis

Article Details

Keywords

Piascledine@, knee osteoarthritis, results, treatment, SYSADOA

References

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