ĐÁNH GIÁ CHẤT LƯỢNG TIÊU BẢN CẮT LẠNH BẰNG MÁY PRESTOCHILL TẠI BỆNH VIỆN E

Abstract

Objectives: To evaluate the quality of frozen-section slides prepared using the PrestoCHILL system at the Department of Pathology, E Hospital. Subjects and methods: A cross-sectional descriptive study on 97 frozen-section specimens from 20 tissue types collected at the Department of Pathology, E Hospital between March and May 2025. Results: The mean age of patients was 52.15 ± 14.75 years. The most frequent specimen types were thyroid gland tumors (38.1%), breast tumors (12.3%), brain tumors (10.3%) and renal tumors (8.24%). The mean turnaround time from specimen receipt to reporting was 13.79 ± 3.85 minutes. Technical error rates were low: tissue folds or wrinkles 5.2%, tearing or tissue loss 3.1%, and tissue fracture 1.0% (mostly mild). Inadequate nuclear staining and inadequate cytoplasmic staining were observed in 3.1% and 6.2% of slides, respectively. Technical problems were mainly encountered in tissues with special structural features such as brain tissue, bone tissue and submandibular, salivary gland tissue… Conclusions: Frozen-section processing with the PrestoCHILL system yielded diagnostic-quality slides with a short turnaround time and low technical error rates. PrestoCHILL appears effective for the majority of intraoperative specimen types, although certain structurally challenging tissues remain prone to specific artifacts