LEFT VENTRICULAR DIASTOLIC DYSFUNCTION IN PATIENTS WITH HEPATITIS B VIRUS-RELATED CIRRHOSIS

Ngô Thị Thanh Loan1,, Phạm Thị Hồng Thi2, Đỗ Duy Cường3, Nguyễn Thị Thu Hoài2
1 Hanoi Medical University
2 Vietnam National Heart Institute, Bach Mai Hospital
3 Department of Infectious Diseases, Bach Mai Hospital

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Abstract

Objjectives: Study of left ventricular diastolic function by echocardiography in patients with hepatitis B virus-related cirrhosis. Patients and methods: Cross-sectional descriptive study was carried out on 68 HBV related cirrhotic patients and 30 matched subjects without a previous history of cardiac in Bach Mai Hospital from July 2020 to August 2021. All study participants underwent cardiac assessment with echocardiography, the parameters assessed included annular e’ velocity (septal e’, ateral e’), average E/e’ ratio, LA maximum volume index (LAVi ml/m2), and peak TR velocity (TRV m/s). Results: Annular e’ velocity was lower, average E/e’ ratio was higher, LAVi and TRV were higher in the HBV related cirrhotic group (p<0.01). 48.5% of patients with HBV related cirrhosis had diastolic dysfunction. Child – Pugh grade C (p<0.001), ascites (p<0.001) and INR ≥ 1.3 (p=0.001) were significant predictors of diastolic dysfunction in patients with hepatitis B virus-related cirrhosis.

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References

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