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EVALUATING THE EPOD (EARLY PREDICTION OF DECOMPENSATION) SCORE IN THE PROGNOSIS OF PATIENTS WITH CIRRHOSIS
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Abstract
Cirrhosis is a common chronic disease with a high mortality rate and hospitalizations frequently due to decompensation with various complications. Early prediction of decompensation is critical and necessary. The EPOD (Early Prediction of Decompensation) score holds significant value in prognosticating decompensation in patients with cirrhosis. Therefore, we conducted a retrospective and prospective descriptive study on 98 patients with cirrhosis at Hanoi Medical University Hospital from November 2019 to July 2025 to evaluate the role of the EPOD score in predicting decompensated cirrhosis. The mean age of the study group was 57.7 ± 9.6 years, with males accounting for 74.5%. Alcohol and hepatitis B were the most common causes of cirrhosis. The mean EPOD score was 11.45 ± 1.94. The EPOD score demonstrated prognostic value for decompensation in cirrhosis patients after two years, with an AUROC of 0.832 (p=0.000) and a cut-off point of 12.078. The EPOD score showed higher reliability compared to MELD, PALBI, or Child-Pugh scores in predicting the risk of decompensation. The EPOD score is significant in predicting decompensation within two years in patients with cirrhosis.
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Keywords
: EPOD, decompensated cirrhosis, prognosis, score.
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