PROGNOSTIC VALUE OF THE GWTG-HF RISK SCORE FOR IN-HOSPITAL MORTALITY IN PATIENTS WITH ACUTE HEART FAILURE

Nhật Huy Đỗ, Minh Kha Nguyễn, Nguyễn Phương Hải Trần, Văn Sỹ Hoàng

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Abstract

Background: Acute heart failure (AHF) is one of the leading causes of hospitalization and is still associated with high in-hospital mortality. Therefore, risk stratification in this patient population is essential. The Get With The Guidelines – Heart Failure (GWTG-HF) risk score, consisting of seven clinical and laboratory variables, has been validated as a reliable tool for predicting in-hospital mortality. However, data on its applicability in Vietnam remain scarce. Objective: To evaluate the prognostic value of the GWTG-HF score for in-hospital mortality among patients with AHF. Methods: A descriptive cross-sectional study with analytic components was conducted in patients with AHF admitted to the Department of Cardiology, Cho Ray Hospital, between October 2024 and June 2025. Results: A total of 329 patients were included. The median age was 63 years (IQR 51 – 73), and 55.3% were male. The in-hospital mortality rate was 8.2%. The GWTG-HF score demonstrated fair predictive ability for in-hospital mortality, with Area Under the Curve (AUC) of 0.72 (95% CI: 0.62 – 0.82). The optimal cut-off value identified by the Youden Index was 44, corresponding to a sensitivity of 74.1%, specificity of 67.2%, positive predictive value of 16.8%, and negative predictive value of 96.7%. Conclusion: The GWTG-HF score provides acceptable predictive performance for in-hospital mortality in patients with acute heart failure in Vietnam, with an AUC of 0.72

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References

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