CLASSIFICATION OF EPILEPSY IN CHILDREN AT CHILDREN’S HOSPITAL 2, HO CHI MINH CITY

Thị Hồng Hạnh Trần, Thị Khánh Vân Lê, Lê Trung Hiếu Nguyễn, Hiếu Anh Bùi, Thất Hoàng Tôn, Thị Mỹ Tiên Huỳnh

Main Article Content

Abstract

Objective: To classify seizure types and epilepsy syndromes according to the International League Against Epilepsy (ILAE) Classification in children aged 1 month to 5 years newly diagnosed with epilepsy. Methods: A cross-sectional descriptive study was conducted on children aged 1 month to 5 years who were newly diagnosed with epilepsy at the Neurology Department of Children's Hospital 2 from January 1, 2024, to July 31, 2024. Results: A total of 137 childrens met the inclusion criteria and were enrolled in the study. The majority of seizure types (97.3%) could be classified according to the 2017 ILAE classification, with focal seizures being the most prevalent (42.2%). Epilepsy syndromes could be identified in 24.8% of cases, with infantile spasms being the most common, accounting for 16.1%. The etiology of epilepsy was identified in 23.4% of patients. Conclusion: The 2017 ILAE Seizure Classification and the 2022 ILAE Epilepsy Syndrome Classification can be applied in the clinical settings of Vietnam to enhance the quality of diagnosis and treatment, improving prognosis, especially in vulnerable young children.

Article Details

References

1. Lê Thị Khánh Vân (2011). Phân loại và điều trị động kinh trẻ em ở bệnh viện Nhi đồng 2 thành phố Hồ Chí Minh. Luận án Tiến sĩ y học. Đại học Y dược thành phố Hồ Chí Minh.
2. Fisher R. S., Cross J. H., French J. A., et al. (2017). Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia. Apr; 58(4):522-530. doi:10.1111/epi.13670
3. Wirrell E. C., Nabbout R., Scheffer I. E., et al. (2022). Methodology for classification and definition of epilepsy syndromes with list of syndromes: Report of the ILAE Task Force on Nosology and Definitions. Epilepsia. Jun 2022;63(6):1333-1348. doi:10.1111/epi.17237
4. Hoàng Châu Bảo Đính Lê Văn Tuấn. (2018). Tỉ lệ các cơn động kinh ở bệnh nhân trẻ em theo phân loại cơn động kinh 2017 của Liên hội Quốc tế Chống Động kinh. Luận văn Bác sĩ Nội trú. Đại học Y dược thành phố Hồ Chí Minh.
5. Aaberg K. M., Suren P., Soraas C. L., et al. (2017). Seizures, syndromes, and etiologies in childhood epilepsy: The International League Against Epilepsy 1981, 1989, and 2017 classifications used in a population-based cohort. Epilepsia. Nov 2017;58(11): 1880-1891. doi:10. 1111/epi.13913
6. Ackermann S., Le Roux S., Wilmshurst J. M. (2019). Epidemiology of children with epilepsy at a tertiary referral centre in South Africa. Seizure. Aug 2019;70:82-89. doi:10.1016/j.seizure.2019. 06.018
7. Sharma S., Anand A., Garg D., et al. (2020). Use of the International League Against Epilepsy (ILAE) 1989, 2010, and 2017 Classification of Epilepsy in children in a low-resource setting: A hospital-based cross-sectional study. Epilepsia Open. Sep 2020;5(3): 397-405. doi:10.1002/epi4. 12401
8. Coryell J., Gaillard W. D., Shellhaas R. A., et al. (22018011). Neuroimaging of Early Life Epilepsy. Pediatrics. Sep 2018;142(3)doi:10.1542/ peds.2018-0672