MAGNETIC RESONANCE IMAGING FEATURES OF DUCTAL CARCINOMA IN SITU OF THE BREAST

Xuân Thắng Ngô, Văn Thi Nguyễn, Tiến Lưu Đoàn

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Abstract

Objective: This study aims to describe the MRI characteristics of ductal carcinoma in situ (DCIS) of the breast using a 1.5 Tesla MRI system. Subjects and Methods: A cross-sectional descriptive study was conducted involving 195 breast cancer patients at the Diagnostic Imaging Center, K Hospital, from January 2024 to May 2025. The MRI features of both DCIS and invasive breast cancer lesions were analyzed and compared with histopathological findings. Results: The study included 195 patients with a total of 196 breast cancer lesions. Among these, DCIS accounted for 15.8% of the cases. DCIS lesions demonstrated a high prevalence of non-mass enhancement and progressive/plateau-type kinetic curves, observed in 58.1% and 67.7% of cases, respectively (p < 0.05). The mean apparent diffusion coefficient (ADC) value of DCIS lesions was significantly higher than that of invasive breast cancer lesions (1.23 ± 0.24 × 10⁻³ mm²/s vs. 0.91 ± 0.21 × 10⁻³ mm²/s, p < 0.05). The area under the ROC curve (AUC) for diagnosing DCIS was 0.854. At the ADC threshold of 0.927 × 10⁻³ mm²/s, the sensitivity and specificity were found to be 96.8% and 60%, respectively. Conclusion: Non-mass enhancement, progressive/plateau kinetic curve patterns, and ADC values above 0.927 × 10⁻³ mm²/s are imaging features indicative of DCIS.

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References

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