HỘI CHỨNG CHUYỂN HÓA VÀ GAN NHIỄM MỠ KHÔNG DO RƯỢU Ở BỆNH NHÂN CAO TUỔI ĐẾN KHÁM TẠI BỆNH VIỆN QUÂN Y 175

Abstract

Background: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the elderly and is closely associated with metabolic syndrome. The coexistence of these two conditions not only increases the risk of liver disease progression but also raises the incidence of cardiovascular events and overall mortality. Objective: To investigate the prevalence of insulin resistance and its association with NAFLD in patients aged ≥ 60 years. Method: A cross-sectional study was conducted on 404 patients aged ≥ 60 years who visited the Senior Officials Clinic at Military Hospital 175 from August 2024 to June 2025. Result: The prevalence of metabolic syndrome was 46.3%, significantly higher in the NAFLD group compared to those without NAFLD (66.4% vs. 24.1%; p < 0.001), and increased progressively with disease severity. Components such as hyperglycemia, elevated triglycerides, low HDL-c, and central obesity were more common in the NAFLD group. Moreover, metabolic indices such as fasting glucose, HbA1c, and triglycerides tended to increase, while HDL-c decreased, in accordance with NAFLD severity. Conclusion: Metabolic syndrome is strongly associated with NAFLD in elderly patients. Early detection and management of its components are essential strategies in preventing and managing NAFLD in this population.