ĐÁNH GIÁ KẾT QUẢ ĐIỀU TRỊ VIÊM LỒI CẦU NGOÀI XƯƠNG CÁNH TAY BẰNG LIỆU PHÁP TIÊM COLLAGEN TRỌNG LƯỢNG PHÂN TỬ THẤP

Abstract

Low-molecular-weight collagen injection has been increasingly applied in the management of musculoskeletal disorders, including lateral epicondylitis. Methods: We conducted a prospective interventional study on 39 patients diagnosed with lateral epicondylitis at Hanoi Medical University Hospital between June 2024 and August 2025. All patients received low-molecular-weight collagen injections. Clinical outcomes were assessed at baseline, 4 weeks, and 8 weeks after treatment using the Visual Analogue Scale (VAS), Quick Disabilities of the Arm, Shoulder and Hand (QDASH), and Patient-Rated Tennis Elbow Evaluation (PRTEE). Results: Significant improvements were observed after 8 weeks of treatment. The mean VAS score decreased from 7.03 ± 0.87 to 1.67 ± 0.84, and the mean QDASH score from 71.15 ± 7.31 to 19.33 ± 6.78. Elbow function also improved, with the mean total PRTEE score decreasing from 69.08 ± 7.50 to 15.12 ± 2.90. All changes were statistically significant (p < 0.05). Mild transient pain at the injection site occurred in 5.13% of patients, while no serious adverse events were recorded. Overall, 89.8% of patients reported satisfaction with treatment. Conclusion: Low-molecular-weight collagen injection is effective in reducing pain and improving elbow function in patients with lateral epicondylitis, with a good safety profile and high patient satisfaction.