KẾT QUẢ ĐIỀU TRỊ TÁO BÓN CHỨC NĂNG BẰNG PHÁC ĐỒ SỬ DỤNG POLYETHYLENE GLYCOL 3350 Ở TRẺ EM TỪ 6 THÁNG ĐẾN 6 TUỔI TẠI BỆNH VIỆN ĐA KHOA THÀNH PHỐ VINH

Abstract

Constipation is a common gastrointestinal disorder in children, with functional constipation accounting for 90–95% of cases. Aims: To evaluate the efficacy of polyethylene glycol (PEG) 3350 regimen in management of functional constipation in children aged 6 months to 6 years at Vinh City General Hospital. Materials and Methods: A prospective, interventional, uncontrolled study was conducted on 62 children aged 6 months to 6 years who were diagnosed with functional constipation according to Rome IV criteria at Vinh City General Hospital from August 1, 2024, to July 31, 2025. Results: The mean defecation frequency increased significantly from 2.5 ± 1.6 times/week before treatment to 4.0 ± 1.6, 4.9 ± 1.5, and 5.5 ± 1.4 times/week at 1, 2, and 3 months after treatment, respectively (p < 0.001). After 3 months, 93.5% of children passed soft stools. Clinical symptoms such as anal pain, straining during defecation; stool-withholding posture, and bloody stools decreased markedly over time (p < 0.01). Treatment efficacy was achieved in 66.1% after 1 month, increasing to 85.5% and 93.5% after 2 and 3 months, respectively (p < 0.001). Adverse effects occurred at a low rate, were mild in severity, and did not affect treatment outcomes. Conclusion: The PEG 3350 regimen demonstrated high efficacy and safety in the management of functional constipation in children, significantly improving clinical symptoms and contributing to enhanced quality of life in pediatric patients.