PREDICTIVE VALUE OF THE FUNC SCORE FOR NEUROLOGICAL FUNCTIONAL OUTCOMES IN PATIENTS WITH ACUTE INTRACEREBRAL HEMORRHAGE”

Thị Thư Nguyễn, Quốc Chính Lương, Anh Tuấn Nguyễn, Hữu Thông Trần

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Abstract

Objective: To evaluate the predictive value of the FUNC score for neurological functional outcomes in patients with acute intracerebral hemorrhage. Methods: This retrospective descriptive study was conducted on 208 patients diagnosed with intracerebral hemorrhage at Bach Mai Hospital from August 2024 to August 2025. Diagnosis was confirmed through clinical examination and non-contrast cranial computed tomography (CT). Clinical variables, CT findings, Glasgow Coma Scale (GCS) scores, and FUNC scores were collected. Functional recovery was assessed at 90 days using the modified Rankin Scale (mRS) through direct clinical evaluation or structured telephone interviews. Data were analyzed using IBM SPSS Statistics version 25. A Receiver Operating Characteristic (ROC) curve was constructed, and the Area Under the Curve (AUC) was calculated to evaluate the prognostic performance of the FUNC score and compare it with the ICH score. Results: At the 90-day follow-up, 63.9% of patients (n = 133) had poor outcomes (mRS90 > 2), while 36.1% (n = 75) achieved favorable outcomes (mRS90 ≤ 2). A strong negative correlation was observed between FUNC scores and mRS90 scores (r = -0.783, p < 0.001). With an AUC of 0.897 and an optimal FUNC cut-off score of 9, the FUNC score demonstrated high predictive accuracy for favorable outcomes (mRS ≤ 2), achieving a sensitivity of 89.3% and a specificity of 81.2%. Conclusion: The FUNC score demonstrates excellent prognostic accuracy in predicting functional outcomes in patients with acute intracerebral hemorrhage and should be considered a valuable tool in both clinical practice and future research.

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References

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