ĐÁNH GIÁ ĐẶC ĐIỂM CÁC RỐI LOẠN ĐÔNG MÁU, CẦM MÁU Ở BỆNH NHÂN XƠ GAN ĐIỀU TRỊ TẠI TRUNG TÂM Y TẾ THANH BA

Abstract

Objective: This study aims to evaluate the characteristics of coagulation and hemostasis disorders in cirrhotic patients treated at Thanh Ba Medical Center and analyze the correlation between the degree of liver fibrosis and coagulation indices. Methods: A cross-sectional descriptive study was conducted on 51 cirrhotic patients from January 2023 to December 2024. Patients underwent clinical evaluation, coagulation tests (PT, INR, aPTT, fibrinogen, D-dimer), and assessment of liver fibrosis using the Metavir scoring system. Results: Prothrombin time (PT) was prolonged (17.2 ± 3.5 seconds), INR increased (1.82 ± 0.45), aPTT extended (41.5 ± 8.3 seconds), fibrinogen decreased (1.8 ± 0.6 g/L), and D-dimer levels were elevated (1.2 ± 0.5 mg/L). Coagulation indices showed a strong correlation with the severity of liver fibrosis: the more advanced the fibrosis, the more severe the coagulation disorders. Conclusion: Cirrhotic patients are at high risk of both bleeding and thrombotic disorders. Monitoring coagulation parameters is essential for risk assessment and therapeutic management.