THE CORRELATION BETWEEN CLINICAL SYMPTOMS, PARACLINICAL FINDINGS AND ARRHYTHMIAS IN PATIENTS WITH ACUTE MYOCARDITIS
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Abstract
Myocarditis is a condition with diverse clinical presentations, ranging from asymptomatic cases to critical scenarios such as acute heart failure, arrhythmias, and even death. Arrhythmias often appear with varying severity. Notably, malignant arrhythmias are the leading cause of death in the acute phase for most patients. Objective: To investigate the correlation between clinical symptoms, paraclinical findings and arrhythmias in patients with acute myocarditis. Subjects and Methods: A cross-sectional study was conducted on 51 patients with acute myocarditis treated at the Intensive Care Unit and the National Heart Institute - Bach Mai Hospital from July 2018 to July 2019. Patients underwent examinations, laboratory tests, and 24-48 hour Holter electrocardiogram monitoring. Results: The average age was 36 ± 16 years, with male patients accounting for 41.2%. Malignant arrhythmias were observed in 66.7% of patients, and 39.2% had three or more episodes of arrhythmias. Factors associated with the severity and frequency of arrhythmias included dyspnea, blood pressure, urine output, potassium levels, CK-MB levels, Troponin T levels, NT-proBNP levels, ejection fraction, and the necessity for ECMO support. Among these, 24-hour urine output, CK-MB levels, Troponin T levels, and the need for ECMO treatment were independently associated. Conclusion: Patients with myocarditis exhibit a high incidence of complex arrhythmias. Clinical and paraclinical factors are closely related to the occurrence of these arrhythmias.
Article Details
Keywords
Myocarditis, ECMO, cardiac arrhythmias
References
2. Sagar S., Liu P.P., and Cooper L.T. (2012). Myocarditis. The Lancet, 379(9817), 738–747.
3. Doolan A., Semsarian C., and Langlois N. (2004). Causes of sudden cardiac death in young Australians. Medical Journal of Australia, 180(3), 110–112.
4. Caforio A.L.P., Calabrese F., Angelini A et al. (2007). A prospective study of biopsy-proven myocarditis: prognostic relevance of clinical and aetiopathogenetic features at diagnosis. European Heart Journal, 28(11), 1326–1333.
5. Smith S.C., Ladenson J.H., Mason J.W. et al (1997). Elevations of cardiac troponin I associated with myocarditis. Experimental and clinical correlates. Circulation, 95(1), 163–168.
6. Rockman et al (1991). Acute fulminant myocarditis: Long-term follow-up after circulatory support with left ventricular assist device. American Heart Journal, 121(3), 922–926
7. Punja M., Mark D.G., McCoy J.V. et al (2010). Electrocardiographic manifestations of cardiac infectious-inflammatory disorders. The American Journal of Emergency Medicine, 28(3), 364–377.
8. Koilpillai C., Quiñones M.A., Greenberg B. et al (1996). Relation of ventricular size and function to heart failure status and ventricular dysrhythmia in patients with severe left ventricular dysfunction. American Journal of Cardiology, 77(8), 606–611.
9. D’Aloia A., Faggiano P., Brentana L. et al (2005). Recurrent ventricular fibrillation during a febrile illness and hyperthermia in a patient with dilated cardiomyopathy and automatic implantable cardioverter defibrillator. An example of reversible electrical storm. International Journal of Cardiology, 103(2), 207–208.