ĐẶC ĐIỂM CĂN NGUYÊN VI SINH Ở NGƯỜI CAO TUỔI VIÊM PHỔI NẶNG TẠI BỆNH VIỆN LÃO KHOA TRUNG ƯƠNG NĂM 2023

Abstract

Objective: Description of the etiological characteristics of bacteria causing ventilator-associated pneumonia in the Intensive Care Unit of the National Geriatric Hospital. Method: Cross-sectional, longitudinal follow-up study conducted on 258 patients in the Intensive Care Unit of the National Geriatric Hospital from May 2023 to December 2023. Results: In the 258 patients included in the study, the male/female patient ratio was 2/1, mean age was 79.2 ± 9.1 years old, the highest was 101 years old and the lowest was 70 years old. The majority of cultured specimens gave positive results, accounting for 48.2%. The majority of Gram-negative bacteria staining results will give Gram-negative bacteria culture results. The most common cause of ventilator-associated pneumonia is Gram (-) bacteria, with A. baumannii being the leading cause, followed by K. peumoniae and P.aeruginosa. The common cause of late-onset VPLQTM is A. baumannii alone or two Gram-negative agents in combination. A. baumannii is only sensitive to <10% of most carbapenems, third-generation cephalosporins, quinolones, and 88.2% is intermediate to colistin. K. pneumoniae is still sensitive to 20-30% of carbapenems, third-generation cephalosporins, 40% to amikacin, 70% to fosfomycin, and 60% is intermediate to colistin. P. aeruginosa is still relatively sensitive to many antibiotics in the third-generation cephalosporin, quinolone, and carbapenem groups, and 88.9% is intermediate to colistin. Conclusion: The common cause of severe pneumonia in the elderly is Gram-negative bacteria, led by A. baumannii, followed by K. pneumoniae and P. aeruginosa.