SOLITARY BRAIN METASTASIS FROM LUNG CANCER MIMICKING ENCEPHALITIS: A CASE REPORT AND LITERATURE REVIEW
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Abstract
Differential diagnosis between a solitary brain metastasis and encephalitis can sometimes be challenging due to atypical imaging features and vague clinical symptoms. We report a case of a 42-year-old male patient admitted with symptoms of headache and dizziness, showing a solitary brain lesion in the left frontal region. The lesion was non-edematous, had no clear ring enhancement, and showed no hypervascularity or abnormality on MRI spectroscopy. The patient received symptomatic treatment and follow-up. After 3 months, the lesion progressed, and a biopsy confirmed adenocarcinoma metastatic from the lung. This case highlights the need for caution when evaluating atypical solitary brain lesions and emphasizes the role of systemic screening in suspected metastatic cases.
Article Details
Keywords
brain metastasis, encephalitis, lung cancer brain metastasis
References
2. Stephen F Kralik, Aaron P Kamer và Chang Y Ho (2015), "Diagnostic imaging of intracranial metastasis", Current Problems in Cancer, 39(2), tr. 99-112.
3. Yifei Su, Rui Cheng, Jinxia Guo và các cộng sự. (2024), "Differentiation of glioma and solitary brain metastasis: a multi-parameter magnetic resonance imaging study using histogram analysis", BMC cancer, 24(1), tr. 805.
4. Dan Zhu, Yongjia Shao, Zhangwei Yang và các cộng sự. (2023), "Magnetic resonance imaging characteristics of brain metastases in small cell lung cancer", Cancer Medicine, 12(14), tr. 15199-15206.
5. Dennis Machaku, Happiness Rabiel, Goodluck Ndibalema và các cộng sự. (2023), "A case report of atypical presentation of a solitary brain metastasis from a primary lung cancer in a low resource setting", International Journal of Surgery Case Reports, 111, tr. 108804.
6. Guangyu Wang, Jiying Xu, Yana Qi và các cộng sự. (2019), "Distribution of brain metastasis from lung cancer", Cancer Management and Research, tr. 9331-9338.
7. Whitney B Pope (2018), "Brain metastases: neuroimaging", Handbook of clinical neurology, 149, tr. 89-112.
8. Sanjay K Singh, Norman E Leeds và Lawrence E Ginsberg (2002), "MR imaging of leptomeningeal metastases: comparison of three sequences", American Journal of Neuroradiology, 23(5), tr. 817-821.
9. Sanjay K Singh, Jacob M Agris, Norman E Leeds và các cộng sự. (2000), "Intracranial leptomeningeal metastases: comparison of depiction at FLAIR and contrast-enhanced MR imaging", Radiology, 217(1), tr. 50-53.
10. J Granerod, NWS Davies, W Mukonoweshuro và các cộng sự. (2016), "Neuroimaging in encephalitis: analysis of imaging findings and interobserver agreement", Clinical radiology, 71(10), tr. 1050-1058.