ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ DIỄN BIẾN TỔN THƯƠNG THẬN CẤP Ở BỆNH NHÂN NGỘ ĐỘC CẤP METHANOL

Abstract

Objects: to discribe the clinical features, laboratory characteristics, progession of AKI in patients with acute methanol poisoning. Subjects and Methods: A descriptive tudy included 93 methanol poisoned patients treated at Poison Control Center of Bach Mai Hospital from 01/2017 to 6/2021. Results: The study patients were mainly male (93.5%), the mean age were 48.39 ± 13.41 years old. There were 41 patients with AKI (44.1%) of which AKI level 1 (61%), level 2 (29.3%) and level 3 (9.7%). In the AKI group: APACHE II score 28.61±6.17, SOFA 9.51±3.47, Glasgow 5.8± 3.74, tachycardia 60.3%, shock 75%, systemic volume depletion 69.8%, oliguria 72.5%, respiratory failure 57.6%, hyperkalemia 73.7%, rhabdomyolysis 90.9%, severe metabolic acidosis 100%,  lactate 9.72 ± 4.49, anion gap 43.34 ±7.87. The most severe kidney damage was at the time of admission, on average after poisoning 34.29 ± 13.24 hours, recovery after treatment 10.51 ± 0.54. Mortality rate in AKI patients was was 63.4%, 9.53 times higher than the group without AKI. Conclusion: The study showed clinical features, laboratory, progression of AKI in patients with acute methanol poisoning.