FACTORS ASSOCIATED WITH RECURRENT SHOCK IN OVERWEIGHT AND OBESE CHILDREN AGED 2-16 YEARS WITH DENGUE SHOCK SYNDROME AT CAN THO CHILDREN'S HOSPITAL, 2022-2024
Main Article Content
Abstract
Background: Dengue Shock Syndrome in overweight and obese pediatric patients often presents with severe clinical manifestations, a complex course, and a high risk of developing recurrent or prolonged shock. Objective: To investigate the factors associated with recurrent shock in overweight and obese children aged 2 to 16 years with DSS at Can Tho Children's Hospital from 2022 to 2024. Methods: An analytical cross-sectional study was conducted on 90 overweight and obese pediatric patients, aged 2 to 16 years, diagnosed with DSS and admitted to Can Tho Children's Hospital between June 2022 and April 2024. Results: Patients presenting with right upper quadrant abdominal pain, a pulse pressure of ≤10 mmHg, shock onset on or before day 5 of illness, and hepatomegaly had a significantly higher risk of recurrent shock. A rising hematocrit (Hct) after 6 hours of fluid resuscitation, hypoalbuminemia, and coagulopathy were also found to be associated with recurrent shock in this patient group. Conclusion: Early clinical warning signs, such as right upper quadrant abdominal pain and narrow pulse pressure, along with adverse laboratory findings including a non-responsive Hct after fluid resuscitation, hypoalbuminemia, and coagulopathy, are valuable prognostic factors strongly associated with the risk of recurrent shock in overweight and obese pediatric patients with DSS.
Article Details
Keywords
Dengue shock syndrome, overweight, obesity, Can Tho.
References
2. Nguyễn Thị Diệu Linh, Tăng Chí Thượng và cs. (2017), "Điều trị sốt xuát huyết Dengue trẻ em tại bệnh viện quận Tân Phú Thành phố Hồ Chí Minh năm 2015-2016", Tạp chí Y học Thành phố Hồ Chi Minh, 21(3), tr.182-186.
3. Lý Hoa Anh Minh, Trần Văn Minh (2024), "Đánh giá đáp ứng điều trị albumin cho bệnh nhi sốt xuất huyết Dengue nặng tại Khoa Nhiễm Bẹnh viện Nhi Đồng Thành Phố", Tạp chí Nhi khoa, 17(1), tr. 63-69.
4. Văn Thị Cẩm Thanh (2017), Đặc điểm dịch tễ, lâm sàng, cận lâm sàng và điều trị bệnh nhân sốt xuất huyết Dengue nặng có sốc tại bệnh viện Nhi Đồng 2 từ 1/1/2015 đến 31/12/2016, Luận văn tốt nghiệp bác sĩ nội trú, Đại học Y Dược Thành phố Hồ Chí Minh.
5. Centers for Disease Control and Prevention (2021), About Child & Teen BMI, truy cập ngày May 25-2022, tại trang web https://www.cdc.gov/ healthyweight/assessing/bmi/childrens_bmi/about_childrens_bmi.html.
6. Scott B. Halstead (2020), Dengue Fever, Dengue Hemorrhagic Fever, and Severe Dengue, Nelson Textbook of Pediatrics, vol Edition 21st, Elsevier Inc.pp.1760-1764.
7. Lam Phung Khanh, Tam Dong Thi Hoai, et al (2013), "Clinical characteristics of dengue shock syndrome in Vietnamese children: a 10-year prospective study in a single hospital", Clinical infectious diseases, 57(11), pp.1577-1586.