PROGNOSTIC VALUE OF THE HAPS AND BISAP SCORING SYSTEMS IN PREDICTING THE SEVERITY IN ACUTE PANCREATITIS

Công Long Nguyễn, Thị Quỳnh Anh Trần, Việt Hằng Đào

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Abstract

Objective: Evaluation of HAPS and BISAP Scores in Predicting Severity of Acute Pancreatitis Patients at Bach Mai Hospital, 2024-2025. Materials and Methods: A cross-sectional study of 120 patients diagnosed with acute pancreatitis and treated at the Gastroenterology and Hepatology Center, Bach Mai Hospital, from November 2024 to June 2025. The HAPS and BISAP scores were assessed within the first 24 hours. Results: The HAPS score demonstrated a fair prognostic value for predicting the severity of acute pancreatitis, with an area under the ROC curve (AUC) of 0.752 (95% CI: 0.672–0.878). At the cut-off value of HAPS = 3 points, the sensitivity was 61.1%, specificity 84.3%, positive predictive value (PPV) 49.7%, and negative predictive value (NPV) 92.5%. The BISAP score demonstrated a good prognostic value for predicting the severity of acute pancreatitis, with an AUC of 0.928 (95% CI: 0.878–0.978). At the cut-off value of BISAP = 3 points, the sensitivity was 81.3%, specificity 90.4%, PPV 66.5%, and NPV 96.9%. The results were statistically significant with p < 0.001. Conclusion: The BISAP score has a better prognostic value than the HAPS score in predicting the severity of acute pancreatitis, particularly within the first 24 hours of hospitalization.

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References

1. Gao W, Yang HX, Ma CE. The Value of BISAP Score for Predicting Mortality and Severity in Acute Pancreatitis: A Systematic Review and Meta-Analysis. PLoS One. 2015;10(6):e0130412. doi:10.1371/journal.pone.0130412.
2. Oskarsson V, Mehrabi M, Orsini N, et al. Validation of the harmless acute pancreatitis score in predicting nonsevere course of acute pancreatitis. Pancreatology. 2011;11(5):464-468. doi:10.1159/000331502.
3. Wu BU, Johannes RS, Sun X, Tabak Y, Conwell DL, Banks PA. The early prediction of mortality in acute pancreatitis: a large population-based study. Gut.2008;57(12):1698-1703. doi:10.1136/gut.2008.152702.
4. Banks PA, Bollen TL, Dervenis C, et al. Classification of acute pancreatitis--2012: revision of the Atlanta classification and definitions by international consensus. Gut.2013;62(1) :102-111. doi:10.1136/gutjnl-2012-302779.
5. Yi Zhao, Xia W, Lu Y, Chen W, Zhuang Y. Predictive value of the C-reactive protein/albumin ratio in severity and prognosis of acute pancreatitis. Front Surg. 2023; 9:1026604. doi:10.3389/fsurg.2022.1026604.
6. Nguyễn Văn Chi, Nguyễn Anh Tuấn, Trần Văn Đồng. Giá trị của thang điểm BISAP trong dự đoán mức độ nặng và tử vong của bệnh nhân viêm tụy cấp. Tạp chí Y học Việt Nam. 2024;539(1B). doi:10.51298/vmj.v539i1B.9958.
7. Gupta D, Mandal NS, Arora JK, Soni RK. Comparative Evaluation of Harmless Acute Pancreatitis Score (HAPS) and Bedside Index of Severity in Acute Pancreatitis (BISAP) Scoring System in the Stratification of Prognosis in Acute Pancreatitis. Cureus. 2022 Dec 15;14(12):e32540. doi:10.7759/cureus.32540.
8. Lê Thị Ngọc Sương, Trần Phạm Chí, Trần Văn Huy. Nghiên cứu giá trị của phối hợp thang điểm HAP và BISAP trong đánh giá độ nặng ở bệnh nhân viêm tuỵ cấp. Tạp chí Y Dược học-Trường Đại học Y Dược Huế. 2019;9(1):96-100. doi:10.34071/jmp.2019.1.15.
9. Bhoi PR, Sethy MK, Jena AK, Mallick SN, Mishra CR, Chakraborty S, Gond S. A comparative study between BISAP score and HAPS score as predictors of severity in acute pancreatitis. J Cardiovasc Dis Res. 2025;16(3): 252–264. doi:10.48047/.
10. Phùng Thị Quỳnh Hoa, Diệp Quảng Minh, Hồ Tấn Phát. Đánh giá giá trị của CRP so với BISAP trong tiên lượng mức độ nặng ở bệnh nhân viêm tuỵ cấp. Tạp chí Y học Cộng đồng Việt Nam. 2025;66(2):56–63. doi:10.52163/yhc.v66i2.2094.