NEW-ONSET FIBRILLATION AND ASSOCIATION WITH TREATMENT OUTCOMES IN SEPTIC SHOCK PATIENTS

Mạnh Hùng Đỗ, Thái Dũng Phạm, Văn Ba Đặng, Tiến Dũng Lê, Minh Dương Vũ, Quang Huy Nguyễn, Đắc Khôi Nguyễn, Tích Lộc Hoàng, Văn Nghĩa Bùi

Main Article Content

Abstract

Objectives: To evaluate the new-onset atrial fibrillation in the first 3 days after diagnosis of septic shock and its association with treatment outcomes in septic shock patients. Materials and method: Prospective Descriptive Study on 54 septic shock patients treated in the Medical Intensive Care Department - Center of Emergency, Intensive Care Medicine and Clinical Toxicology - 103 Military Hospital - Vietnam Military Medical University. Results: Septic shock patients with new-onset atrial fibrillation accounted for 53.7%. In the first 3 days, the group with new-onset atrial fibrillation had a mortality rate of 41.4%, which was statistically significantly higher than the group without new-onset atrial fibrillation (8%) with OR=8.12 (95% CI: 1.60-41.14, p<0.01). Similarly, in the first 7 days, the group with new-onset atrial fibrillation had a mortality rate of 62.1%, which was statistically significantly higher than the group without atrial fibrillation (24%) with OR=5.18 (95% CI: 1.58-16.95, p<0.01). However, there was no difference between the mortality rate within 28 days in the groups with and without new-onset atrial fibrillation (p>0.05). Conclusion: New-onset atrial fibrillation was a common arrhythmia in septic shock patients. The group with new-onset atrial fibrillation had a higher risk of death than the group without atrial fibrillation in the first 3 and 7 days after diagnosis.

Article Details

References

1. Phú V. Đ. et al. (2024) Đặc điểm lâm sàng, cận lâm sàng và căn nguyên gây sốc nhiễm khuẩn tại bệnh viện Nhiệt đới Trung ương. Tạp chí Y học Việt Nam. 535 (1).
2. Thủy N. T. et al. (2021) Đặc điểm lâm sàng, cận lâm sàng và một số yếu tố liên quan đến kết quả điều trị bệnh nhân sốc nhiễm khuẩn tại bệnh viện Trung ương Thái Nguyên. Tạp chí Y học Việt Nam. 498 (1).
3. Aibar J. et al. (2021) New-Onset Atrial Fibrillation in Sepsis: A Narrative Review. Semin Thromb Hemost. 47 (1): 18-25.
4. Corica B. et al. (2022) Prevalence of New-Onset Atrial Fibrillation and Associated Outcomes in Patients with Sepsis: A Systematic Review and Meta-Analysis. J Pers Med. 12 (4).
5. Elhadad M. A. et al. (2025) Prevalence, Outcomes, and Risk Factors of New-Onset Atrial Fibrillation in Critically Ill Patient with Sepsis and Septic Shock %J Benha Medical Journal.
6. Huo Y. et al. (2025) Risk Factors and Prognosis of New-Onset Atrial Fibrillation in Sepsis. JACC: Advances. 4 (4): 101681.
7. Singer M. et al. (2016) The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). Jama. 315 (8): 801-810.
8. Xiao F. P. et al. (2021) Outcomes of new-onset atrial fibrillation in patients with sepsis: A systematic review and meta-analysis of 225,841 patients. Am J Emerg Med. 42 (23-30).