CLINICAL FEATURES AND TREATMENT OUTCOMES OF DUANE RETRACTION SYNDROME

Thanh Dũng Đặng, Văn Huy Nguyễn, Thị Quế Anh Vũ, Thị Thu Hằng Trần

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Abstract

Purpose: This study was conducted to describe the clinical characteristics and evaluate the treatment outcomes of Duane retraction syndrome at the Vietnam National Eye Hospital. Methods: A non-controlled interventional descriptive study was performed on a series of patients diagnosed with Duane retraction syndrome. A convenient sample size was selected in accordance with the study criteria. Results: Among 14 patients included, the mean age at surgery was 11.7 years (range: 4–30 years). Strabismus with limitation of ocular motility causing abnormal head posture was observed in 92.86% of patients. Characteristic motility disorders such as globe retraction were found in 100% of cases, while overshoots occurred in 64.3%. The most common refractive error was mild to moderate hyperopia, and 14.29% of patients had amblyopia, all of whom received amblyopia treatment prior to surgery. The mean preoperative deviation was 16.7 prism diopters, with the left eye more frequently affected (66.67%) than the right eye (33.33%). The main surgical techniques included medial or lateral rectus recession, with or without Y-splitting of the lateral rectus. After 3 and 6 months of follow-up, 100% of patients showed good correction of ocular deviation and abnormal head posture. Overshoot was effectively managed by Y-splitting in 88.9% of cases. Globe retraction improved only partially, as surgery reduced severity but did not completely eliminate symptoms. All patients reported satisfaction with surgical outcomes. Conclusion: Duane retraction syndrome is a relatively rare congenital strabismus syndrome caused by anomalous innervation of the extraocular muscles. Clinically, it presents with abnormal head posture and characteristic ocular motility disorders. Surgical treatment proved effective in correcting these abnormalities, with low intraoperative and postoperative complication rates

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References

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