VALUE OF PALBI SCORE IN PROGNOSIS OF GASTROINTESTINAL BLEEDING DUE TO RUPTURE OF ESOPHAGEAL VARICOSES IN PATIENTS WITH LIVER CIRRHOSIS TREATED AT THAI NGUYEN NATIONAL HOSPITAL
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Abstract
Objective: To evaluate the prognostic value of the PALBI score in predicting gastrointestinal bleeding due to ruptured esophageal varices in cirrhotic patients treated at Thai Nguyen National Hospital. Subjects and Methods: A cross-sectional descriptive study was conducted on 178 cirrhotic patients diagnosed with gastrointestinal bleeding from ruptured esophageal varices confirmed by esophagogastroduodenoscopy, from July 2024 to July 2025 at Thai Nguyen National Hospital. Results: The PALBI score demonstrated excellent prognostic performance for in-hospital mortality (AUROC = 0.82; 95% CI: 0.75–0.89; p = 0.000). At the cut-off value of –0.79, the sensitivity was 81.1% and specificity was 86.6%. The PALBI score also showed excellent predictive value for early rebleeding (AUROC = 0.81; 95% CI: 0.70–0.91; p = 0.000). At the cut-off value of –0.71, the sensitivity was 80.9% and specificity was 87.5%. Conclusion: The PALBI score is a useful prognostic tool with high predictive accuracy for both early rebleeding and in-hospital mortality in cirrhotic patients with ruptured esophageal varices. Incorporating PALBI into clinical practice may enhance early risk stratification, support timely therapeutic decision-making, and contribute to improved patient outcomes
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Keywords
PALBI, rebleeding, mortality, cirrhosis, gastrointestinal bleeding.
References
2. N. V. Chung, Đ. Đ. Tiến, and D. Q. Huy, "Nghiên cứu giá trị của thang điểm PALBI trong tiên lượng xuất huyết tiêu hóa cấp do vỡ giãn tĩnh mạch thực quản ở bệnh nhân xơ gan," (in vi), Journal of 108-Clinical Medicine and Phamarcy, 2022.
3. S. Roayaie et al., "PALBI-an objective score based on platelets, albumin & bilirubin stratifies HCC patients undergoing resection & ablation better than Child's classification," in Hepatology, 2015, vol. 62, pp. 631A-632A: Wiley-blackwell 111 river st, hoboken 07030-5774, nj USA.
4. N. T. H. Trâm and V. H. M. Công, "Giá trị điểm PALBI dự đoán các biến cố kết cục trong vòng 6 tuần ở bệnh nhân xơ gan có xuất huyết tiêu hóa trên do tăng áp tĩnh mạch cửa," (in vi), Tạp chí Y học Việt Nam, vol. 534, no. 2, 2024.
5. V. T. N. Bích and N. T. Vân Hồng, "Sự thay đổi và giá trị tiên lượng tử vong trong 30 ngày của chỉ số ALBI và PALBI ở bệnh nhân xơ gan có biến chứng," (in vi), Tạp chí Y học Việt Nam, vol. 535, no. 1, 2024.
6. M. S. Faisal, T. Singh, H. Amin, and J. M. Esfeh, "Role of platelet-albumin-bilirubin score in predicting re-bleeding after band ligation for acute variceal hemorrhage," (in eng), World J Hepatol, vol. 12, no. 10, pp. 880-882, Oct 27 2020.
7. Swarna, M. Ramamoorthy, R. Kini, C. Annasamy, M. Kalyanasundaram, and S. Immaneni, "Platelet-albumin-bilirubin score - a risk stratification scoring system to predict outcome of acute variceal bleeding in patients with cirrhosis," (in eng), Eur J Gastroenterol Hepatol, vol. 35, no. 9, pp. 1044-1048, Sep 1 2023.
8. O. Elshaarawy, N. Allam, E. Abdelsameea, A. Gomaa, and I. Waked, "Platelet-albumin-bilirubin score-a predictor of outcome of acute variceal bleeding in patients with cirrhosis," (in eng), World journal of hepatology, vol. 12, no. 3, p. 99, 2020.