VAI TRÒ CỦA TRẮC NGHIỆM ĐÁNH GIÁ NHẬN THỨC MOCA TRONG TẦM SOÁT SA SÚT TRÍ TUỆ MẠCH MÁU

Abstract

Objective: This study aimed to evaluate the role of the Montreal Cognitive Assessment (MoCA) in screening for vascular dementia .Methods: A cross-sectional descriptive study was conducted on 152 patients with cerebrovascular disease at the National Geriatric Hospital from October 2024 to July 2025. All participants underwent cognitive screening using the MoCA and were diagnosed with vascular dementia according to DSM-5 criteria. Results: The study included 152 patients with cerebrovascular disease, with a mean age of 73.41 ± 8.09 years. Among these, 21.7% were diagnosed with dementia, and 78.3% were non-demented. The mean MoCA score in the dementia group was 13.82 ± 1.86, significantly lower than that of the non-demented group (22.61 ± 3.40, p < 0.01). All cognitive domains assessed by MoCA including visuospatial/executive function, naming, attention, language, abstraction, memory, and orientation showed statistically significant differences between the two groups. Receiver Operating Characteristic (ROC) curve analysis demonstrated excellent discriminative ability of the MoCA, with an Area Under the Curve (AUC) of 0.994 (95% CI: 0.985–1.000, p < 0.001). The optimal cut-off score was determined to be 16/17, with a Youden Index of 0.944. At this threshold, MoCA achieved a sensitivity of 96.7%, specificity of 97.5%, positive predictive value of 91.4%, and negative predictive value of 99.1%. Conclusion: The MoCA is a highly sensitive and specific cognitive screening tool for the detection of vascular dementia