TREATMENT OUTCOMES OF COLON CANCER IN YOUNG PATIENTS AT K HOSPITAL IN PERIOD 2016-2020

Nguyễn Thị Mai1,, Vũ Hồng Thăng1,2
1 Hanoi Medical University
2 K Hospital

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Abstract

Aims: To evaluatethe treatment outcomes of colon cancer in young patients at K hospital in period 2016-2020. Patients and methods:Retrospective study combined prospective study on the young patients who were 30 years or younger and diagnosed with colon cancer, treated at K hospital, in 2016-2020. Results:The rates of complete response andrecurrent diseasewere 65,3% and 20,4%, respectively. The rate of recurrent disease was related to theCEA concentration. The rate of OS at5 years was 37%. The median5-year OSwas 28,1±8,26 months. There was significant difference in 5-year OSamong stages of disease. Conclusion: The rates of complete response andrecurrent disease were 65,3 and 20,4% and related to the CEA concentration. The rates of5-year OSwas 37%. The relationship between 5-year OS and stagewas significant.

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References

1. F. Bray, J. Ferlay, I. Soerjomataram và cộng sự (2018). Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin, 68(6), 394-424.
2. O’Connell JB, Maggard MA, Livingston, et all. (2004). Colorectal cancer in the young. Am J Surg 187: 343-348.
3. Kam MH, Eu KW, Barben CP, Seow-Choen F. Colorectal cancer in the young: a 12-year review of patients 30 years or less. Colorectal Dis. 2004;6(3):191-194. doi:10.1111/j.1463-1318.2004.00596.x
4. Parramore JB, Wei JP, Yeh KA. Colorectal cancer in patients under forty: presentation and outcome. Am Surg 1998; 64: 563–8.
5. Rodriguez-Bigas MA, Mahoney MC, Weber TK, Petrelli NJ. Colorectal cancer in patients aged 30 years or younger. Surg Oncol. 1996;5(4):189-194. doi:10.1016/S0960-7404(96)80043-0
6. Trần Vi Doanh (2005). "Nghiên cứu một số yếu tố nguy cơ di căn xa của ung thư đại trực tràng tại bệnh viện K Hà Nội từ 2003 đến 2004", Luận văn Thạc sỹ y học, trường Đại học Y Hà Nội.
7. Zhao L, Bao F, Yan J, et al. Poor prognosis of young patients with colorectal cancer: a retrospective study. Int J Colorectal Dis. 2017;32(8):1147-1156. doi:10.1007/s00384-017-280
8. Cancer of the Colon and Rectum - Cancer Stat Facts. SEER. Accessed September 28, 2021. https://seer.cancer.gov/statfacts/html/colorect.htm