XÁC NHẬN GIÁ TRỊ SỬ DỤNG CỦA PHƯƠNG PHÁP BROMOCRESOL GREEN TRONG XÁC ĐỊNH NỒNG ĐỘ ALBUMIN HUYẾT TƯƠNG VÀ VAI TRÒ CỦA XÉT NGHIỆM ALBUMIN TRONG ĐÁNH GIÁ ĐỘ NẶNG TRÊN BỆNH NHÂN VIÊM TUỴ CẤP TẠI BỆNH VIỆN CHỢ RẪY

Abstract

Acute pancreatitis (AP) is a potentially fatal disease, and a low serum albumin concentration is considered a key indicator closely related to its severity. This study, conducted at Chợ Rẫy Hospital, aimed to confirm the reliability of the Bromocresol Green (BCG) assay on the Cobas c702 analyzer and to evaluate the role of albumin in predicting the prognosis of AP. A cross-sectional study on 138 AP patients demonstrated that the BCG method on the Cobas c702 system has high accuracy and reproducibility. Its coefficient of variation (CV%) and bias were both within acceptable limits. The results showed that the mean serum albumin concentration in the AP patient group was 3.52±0.69 g/dL, and 32.5% of them had hypoalbuminemia. This low albumin level was found to correlate with the severity of the disease. In conclusion, the albumin assay using the BCG method on the Cobas c702 analyzer is a reliable tool. Monitoring this indicator can help clinicians promptly assess the severity and clinical prognosis in AP patients, which may lead to improved treatment outcomes and reduced mortality rates.