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CORRELATION BETWEEN HIGH-SENSITIVITY C-REACTIVE PROTEINS LEVELS (hs-CRP) AND SOME BIOCHEMICAL TEST INDEX IN TYPE 2 DIABETES PATIENTS
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Abstract
Background: Prolonged in inflammation causes vascularcomplications in diabetes. If not controlled and treated promptly, the patient can become disabled and die. Blood hs-CRP test as a useful biomarker of chronic vasculitis, in order to support diagnosis, monitor treatment and detect complications effectively for patients with type 2 diabetes. Aim: To examine the correlation between blood hs-CRP levels and some biochemical test index (glucose, HbA1c, total cholesterol, LDL-C, HDL-C and triglyceride) in type 2 diabetes patient. Sample: 238 pepple divided into two groups: group of 118 patients with type 2 diabetes and group of 220 healthy people (control group) having age and gender equivalent to the patient group. Method: A cross-sectional descriptive study. Patients under clinical examination, history abstraction, intravenous blood werw measured levels of hs-CRP, glucose,HbA1c, total cholesterol, LDL-C, HDL-C and triglyceride. Diagnose type 2 diabetes according to ADA 2020. Results: Blood hs-CRP (mg/L) in the patient and control groups were 3,9 ± 1,7 compared to 1,7 ± 1,1mg/L (p<0,001). This difference is statistically significant. Patients with high levels of hs-CRP at high and average rick for heart disease were 99.2%. In which, the percentage of patients at high, medium and low levels were72.9; 26.3 and 0.8 respectively. Blood hs-CRP levels were positive correlated with glucose, HbA1c,total cholesterol, LDL-C and triglyceride, inverse correlated with triglyceride. Conclusion: The blood hs-CRP levels in type 2 diabetes patients were higher than control group. There is a positive correlation between hs-CRP levels in blood with glucose, HbA1c, total cholesterol, LDL-C and triglyceride, nagative correlated with triglyceride.
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Keywords
hs-CRP, type 2 diabetes
References
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