KẾT QUẢ ĐIỀU TRỊ ĐAU SAU ZONA TẠI BỆNH VIỆN DA LIỄU HÀ NỘI BẰNG TIÊM BOTULINUM TOXIN A TẠI CHỖ

Abstract

Objective: To evaluate the results of post-herpetic neuralgia treatment at Hanoi Dermatology Hospital from April 2025 to September 2025 by local injection of Botulinum toxin A. Subjects and methods: Clinical intervention study, non-controlled on 30 patients diagnosed with post-herpetic neuralgia who came to Hanoi Dermatology Hospital for examination and treatment from April 2025 to September 2025 by injection of Botulinum toxin A. Treatment results were evaluated by the improvement in VAS (visual analog scale) scores and patient satisfaction at 2 weeks, 1 month, 2 months, and 3 months after treatment. Results: Compared to before treatment, VAS scores decreased at all time points: 2 weeks, 1 month, 2 months, and 3 months after treatment. VAS scores decreased fastest in the first 2 weeks and then decreased more slowly in the following time points. After 2 weeks, up to 50% of patients achieved a reduction in VAS ≥ 50%, and 3.3% of patients were pain-free (VAS = 0). After 3 months, 100% of patients had a reduction in VAS ≥ 50% and 60% of patients were pain-free. Side effects were mainly local, with no systemic side effects. Locally, all patients experienced local pain with 66.37% of patients experiencing mild pain. 4/6 patients with head, face, and neck lesions (13.3%) experienced bilateral asymmetry side effects. This side effect does not affect function, mainly affects aesthetics. Conclusion: Local injection of botulinum toxin A has high results and is safe in treating post-herpetic neuralgia