UNG THƯ BIỂU MÔ TYPE TUYẾN NƯỚC BỌT NGUYÊN PHÁT Ở PHỔI: NHÂN MỘT TRƯỜNG HỢP HIẾM GẶP TẠI BỆNH VIỆN PHỔI TRUNG ƯƠNG

Abstract

Primary salivary gland–type carcinoma of the lung is a rare neoplasm, accounting for less than 1% of all pulmonary tumors. This tumor arises from the submucosal glands of the trachea or bronchi and shares histological features with salivary gland tumors originating from the head and neck region, as well as from the breast and thymus. The disease is typically seen in middle-aged, non-smoking individuals and can easily be misdiagnosed as pneumonia due to its nonspecific clinical presentation. We report the case of a 39-year-old woman who was admitted with recurrent pneumonia. Chest CT revealed an endobronchial mass in the right intermediate bronchus, leading to inflammation and partial atelectasis of the right lower lobe. Bronchoscopy demonstrated a friable mass almost completely obstructing the bronchial lumen. Histopathology confirmed the diagnosis of low-grade mucoepidermoid carcinoma, a subtype of primary salivary gland-type carcinoma of the lung. Systemic evaluation excluded metastasis from salivary glands. The patient underwent bronchoplastic resection with end-to-end anastomosis combined with paclitaxel-carboplatin chemotherapy. After seven months of follow-up, no recurrence was observed. This case highlights that although primary salivary gland-type carcinoma of the lung is rare, it should be considered in the differential diagnosis of patients with chronic cough or recurrent pneumonia. Complete surgical resection remains the treatment of choice and offers a favorable prognosis, particularly in low-grade mucoepidermoid carcinoma