ĐÁNH GIÁ KẾT QUẢ ĐIỀU TRỊ HỘI CHỨNG THẬN HƯ TIÊN PHÁT Ở TRẺ EM TẠI THÁI NGUYÊN

Abstract

Objective: To assess the outcome of idiopathic nephrotic syndrome at Thai Nguyen. Subject: 30 children with idiopathic nephrotic syndrome were diagnosed and treated at Thai Nguyen national hospital and A hospital from 01/ 2019 to 03/ 2021. Methods: Descriptive cross-sectional study. Results: Males got involved in idiopathic nephrotic syndrome more than females with the ratio male to female of 4/1 (24 male and 6 female). The mean age at was 6.1 years old, group with patients from 5-10 years old were 63,3%. The patients in study with signal edema 100%, hypertension 40%, oligulia 26,7%, the mean of proteinuria 24h was 163,26 mg/kg/24h, severe hypoalbuminemia (average was 17,42 g/l), hypercholestrerolemia (average was 9,76 mmol/l). The ratio patients response with corticosteroid was 76,7% and the mean time response with one was 11,73 days. Recurrence rate after 3 months of treatment was 36.67%, of which mainly patients with combination type (87,5%). Conclusion: The idiopathic nephrotic syndrome usually occurred in male, school age,the main symptoms were edema, severe hypoalbuminemia and hyperproteinuria. Chidren with idiopathic nephrotic syndrome responsed well to corticosteroid. The number of patients with relapse is mainly patients with combination type nephrotic syndrome.