INCIDENCE OF PERITONITIS DUE TO CHOLECYSTITIS AND RELATED RISK FACTORS AT CA MAU GENERAL HOSPITAL, 2023–2024

Ngọc Linh Huỳnh, Thể Tần Nguyễn, Văn Thùy Phù, Văn Hải Nguyễn

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Abstract

Introduction: Peritonitis is a severe complication of acute cholecystitis that can lead to mortality if not intervened in a timely manner. Objective: To determine the incidence of peritonitis due to cholecystitis and its associated factors at Cà Mau General Hospital during the period of 2023-2024. Subjects and Methods: A cross-sectional descriptive study was conducted on 643 patients diagnosed with cholecystitis, with data collected from January 2023 to December 2024. Analysis was performed using Stata 18.0 software and multivariate logistic regression. Results: The incidence of peritonitis was 23.79% (153/643). The study results indicated that 65.94% of patients resided in rural areas; 67.97% were female; 43.23% were aged ≥60 years; the duration from onset to hospitalization was ≥72 hours in 30.64% of cases; leukocyte count ≥15 G/L was observed in 74.80%; and CRP levels >10 mg/L were found in 72.78%. Multivariate logistic regression analysis revealed the following associated factors: rural residency (adjusted OR=1.53; 95% CI: 1.03–2.56; p=0.01), age ≥60 years (1.94; 1.12–2.83; p=0.003), onset >72 hours (2.35; 1.15–3.58; p<0.0001), presence of comorbidities (1.64; 1.31–2.93; p=0.002), leukocyte count >15 G/L (1.48; 1.11–3.43; p=0.009), and CRP >50 mg/L (1.39; 1.14–2.68; p=0.03). Conclusion: Peritonitis due to cholecystitis constitutes a significant proportion. Early diagnosis, hospitalization within <72 hours, management of underlying conditions, and monitoring of inflammatory markers are essential to reduce complications and improve outcomes.

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