ĐẶC ĐIỂM LÂM SÀNG VÀ MỘT SỐ CHỈ SỐ SINH HÓA MÁU Ở BỆNH NHÂN LOẠN THẦN DO RƯỢU ĐẾN KHÁM TẠI PHÒNG KHÁM 103 CẨM KHÊ

Abstract

Aims: To describe the clinical features and biochemical in patients with alcohol-induced psychosis at Clinic 103 Cam Khe. Methods: The study included 36 male patients aged 18 years and older, diagnosed with alcohol-induced psychosis according to ICD-10/DSM-5 criteria, with a history of prolonged alcohol use and onset of psychotic symptoms within the past month. The study was conducted from January 2023 to December 2024. Results: Most patients were aged 40–60, with 83.3% having consumed alcohol for over 10 years. Common symptoms included insomnia (70%), delusions (65%), hallucinations (52%), agitation (45%), and anxiety (38%). Biochemically, elevated liver enzymes were common (mean AST: 85 U/L, ALT: 72 U/L, GGT: 110 U/L), with hyperglycemia in 30.6%, dyslipidemia in 38.9%, and elevated uric acid in 25%. A statistically significant association was found between alcohol use duration >10 years and increased blood glucose, triglycerides, and uric acid levels. Additionally, the daily volume of alcohol consumption was significantly associated with the severity of psychotic symptoms. Conclusion: Alcohol-induced psychosis presents with diverse clinical and biochemical manifestations, closely related to both the duration and amount of alcohol consumption, indicating the need for early detection and timely intervention.