COLORECTAL CANCER IN PREGNANT WOMEN: CASE REPORT AND LITERATURE REVIEW
Main Article Content
Abstract
The incidence of colorectal cancer (CRC) in pregnant women is usually very low. CRC in pregnant women presents many challenges in diagnosis and treatment, requiring multidisciplinary coordination. We recorded a pregnant woman in the 29th week of pregnancy, who came to the clinic because of left lower quadrant abdominal pain accompanied by loose stools 6-7 times/day. The results of abdominal MRI showed thickened colon wall, colonoscopy with biopsy showed moderately differentiated adenocarcinoma. With multidisciplinary coordination, the patient was scheduled for cesarean section and tumor surgery at the 32nd week. Pregnant women with gastrointestinal symptoms are easily confused with physiological changes during pregnancy, so CRC should be considered for differential diagnosis. Paraclinical tests, imaging diagnosis and gastrointestinal endoscopy, if necessary, for early detection and timely treatment to help improve the prognosis of the disease.
Article Details
Keywords
colorectal cancer and pregnant women.
References
2. Shushan A, Stemmer SM, Reubinoff BE, Eid A, Weinstein D. Carcinoma of the colon during pregnancy. Obstet Gynecol Surv. 1992;47(4):222-225. doi:10.1097/00006254-199204000-00002
3. Saif MW. Management of colorectal cancer in pregnancy: a multimodality approach. Clin Colorectal Cancer. 2005;5(4): 247-256. doi:10. 3816/ccc.2005.n.035
4. Ossendorp RR, Silvis R, van der Bij GJ. Advanced colorectal cancer resulting in acute bowel obstruction during pregnancy; a case report. Ann Med Surg (Lond). 2016;8:18-20. doi:10.1016/j.amsu.2016.04.018
5. Bernstein MA, Madoff RD, Caushaj PF. Colon and rectal cancer in pregnancy. Dis Colon Rectum. 1993;36(2): 172-178. doi:10.1007/ BF02051174
6. Fletcher RH. Carcinoembryonic antigen. Ann Intern Med. 1986;104(1): 66-73. doi:10.7326/ 0003-4819-104-1-66
7. Seidman DS, Heyman Z, Ben-Ari GY, Mashiach S, Barkai G. Use of magnetic resonance imaging in pregnancy to diagnose intussusception induced by colonic cancer. Obstet Gynecol. 1992;79(5 ( Pt 2)):822-823.
8. Yaghoobi M, Koren G, Nulman I. Challenges to diagnosing colorectal cancer during pregnancy. Can Fam Physician. 2009;55(9):881-885. Accessed August 26, 2025. https://www.ncbi. nlm.nih.gov/pmc/articles/PMC2743581/
9. Antonelli NM, Dotters DJ, Katz VL, Kuller JA. Cancer in pregnancy: a review of the literature. Part I. Obstet Gynecol Surv. 1996;51(2):125-134. doi:10.1097/00006254-199602000-00022
10. Quaresima P, Saccone G, Pellegrino R, et al. Incidental diagnosis of a pancreatic adenocarcinoma in a woman affected by gestational diabetes mellitus: case report and literature review. Am J Obstet Gynecol MFM. 2021;3(6): 100471. doi:10.1016/j.ajogmf.2021. 100471.