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THYROID EYE DISEASE WITH DYSTHYROID OPTIC NEUROPATHY: A CASE SERIES
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Abstract
Thyroid eye disease (TED) is an autoimmune disorder frequently associated with Graves’ disease and other autoimmune thyroid conditions. Dysthyroid optic neuropathy (DON) is a rare but serious complication that can lead to permanent vision loss if diagnosis and treatment are delayed.¹ Early recognition and timely management significantly improve prognosis, although severe progression may still occur despite appropriate therapy. However, diagnosing DON remains challenging due to atypical clinical manifestations, and the diagnostic criteria remain a matter of debate. We report two cases of Graves’ disease complicated by TED with dysthyroid optic neuropathy at the Vietnam National Eye Hospital, both presenting with severe visual impairment that had initially been missed during endocrine follow-up. Both patients achieved good visual recovery following prompt orbital decompression surgery. These cases highlight the importance of early recognition of DON in TED to improve patient outcomes and quality of life.
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Keywords
Thyroid eye disease, dysthyroid optic neuropathy, thyroid-associated ophthalmopathy, relative afferent pupillary defect.
References
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