ĐÁNH GIÁ TÍNH AN TOÀN VÀ HIỆU QUẢ CỦA KỸ THUẬT KÍCH THÍCH ĐIỆN TRỰC TIẾP XUYÊN SỌ TRÊN BỆNH NHÂN TÂM THẦN PHÂN LIỆT

Abstract

Objective: This study aims to evaluate the safety and efficacy of transcranial direct current stimulation (tDCS) in patients with schizophrenia. Subjects and Methods: One hundred and forty patients with schizophrenia were included in the study: 70 patients were treated with transcranial direct current stimulation (tDCS) combined with medication, and 70 patients were treated with routine medication. This was an interventional study - a randomized, controlled clinical trial. Patients underwent clinical examination and laboratory tests at the time of hospital admission and after 21 days of treatment. Data were processed using SPSS 22.0. Results: The tDCS intervention group showed significant improvement in symptoms such as poverty of speech, slowed thinking, inappropriate affect, insomnia, and loss of appetite, with statistically significant differences compared to the control group. The tDCS technique demonstrated a high safety profile: no serious side effects were recorded; only mild itching and skin irritation at the electrode placement site were reported in some patients. No significant changes were observed in biochemical and hematological indices after treatment. Conclusion: tDCS is an effective and safe therapeutic option for patients with schizophrenia.