EVALUATION OF TREATMENT RESULTS WITH mFOLFOX6 - BEVACIZUMAB REGIMEN IN PATIENTS WITH STAGE IV COLON CANCER
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Abstract
Objectives: To evaluate the results of mFOLFOX6 – Bevacizumab regimen in colon cancer patients with stage IV colon cancer at 108 Military Central Hospital. Subjects and Methods: This is a retrospective descriptive study of 56 stage IV colon cancer patients, who were treated with mFOLFOX6 – Bevacizumab regimen from January 2020 to January 2024 at 108 Military Central Hospital. Results: Objective response rate was 62,1%, median progression-free survival (PFS) was 12 months, median overall survial (OS) was 23,1 months. Several factors were statistically significantly associated with PFS and OS, including tumor progression, CEA levels, number of metastatic sites and response rate. Conclusion: The mFOLFOX6 – Bevacizumab regimen resulted in high objective response rate, promising PFS, OS. Several factors related to PFS and OS include tumor progression, CEA levels, number of metastatic sites and treatment response level with prognostic significance
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Keywords
colon cancer metastasis, mFOLFOX6 – Bevacizumab.
References
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