MEDICATION ADHERENCE AND ASSOCIATED FACTORS AMONG PEDIATRIC EPILEPSY PATIENTS AT HAI PHONG CHILDREN’S HOSPITAL

Văn Trung Nguyễn, Văn Trọng Nguyễn, Thị Khánh Ninh Trần, Thị An Nguyễn, Dương Tùng Anh Đinh

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Abstract

Objective: To describe the status of medication adherence and associated factors among children with epilepsy at Hai Phong Children’s Hospital. Subjects: A total of 86 patients diagnosed with epilepsy and treated at Hai Phong Children’s Hospital from June 1, 2024 to April 30, 2025. Methods: Cross-sectional descriptive study. Results: Among the children with epilepsy, 63.95% were male; 58.14% were older than 10 years, with a mean age of 9.54 ± 4.44 years; and 68.6% resided in suburban areas. Generalized epilepsy accounted for 53.3% of cases. According to the Morisky-8 scale, at one and two months of treatment, the group with high adherence represented the largest proportion (45.35%). By the third month, the rate of high adherence increased slightly to 47.67%. The most common non-adherent behaviors were occasionally forgetting to take medication and having difficulty remembering to take all prescribed doses. Across the three time points, factors associated with higher adherence included: age over 10 years, use of two antiepileptic drugs compared with one, absence of family history of epilepsy, and absence of developmental or language delay. Conclusion: A high level of treatment adherence was observed in the majority of children. The most common non-adherent behaviors were occasionally forgetting medication and difficulty maintaining full dosing. High adherence was associated with age over 10 years, use of two antiepileptic drugs, no family history of epilepsy, and no mental or language developmental delay

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References

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