ANTIMICROBIAL RESISTANCE CHARACTERISTICS OF AIRBORNE PATHOGENIC BACTERIA ISOLATED FROM INTENSIVE CARE UNITS AT THE UNIVERSITY MEDICAL CENTER HO CHI MINH CITY IN 2025

Vũ Hoàng Yến Nguyễn, Hoàng Hải Huỳnh, Thị Hằng Nga Nguyễn, Thanh Tuyền Nguyễn, Thị Yến Nhi Lê, Thúy Vy Đàm, Minh Tuấn Huỳnh

Main Article Content

Abstract

Background: Poor air quality of healthcare-facilities, particularly the presence of airborne pathogens, has been directly linked to an increase of healthcare-associated infections. Objective: To survey of antibiotic resistance of bacterial strains isolated in the air at the Intensive Care Units of the University Medical Center, Ho Chi Minh City. Subjects and methods: Air samples were collected by machine five times, periodically every week in three Intensive Care Units. A descriptive cross-sectional method was used for analysis. Results: In 150 air samples collected, 76 bacterial strains were isolated and identified. Gram-positive bacteria predominated (77.6%); of which Staphylococcus epidermidis was the most common (43.4%). Pathogens included: Acinetobacter baumannii (9.2%); Enterobacteriaceaes (7.8%);  Staphylococcus aureus (7.9%). The average rate of CRAB (Carbapenem-Resistant Acinetobacter baumannii) was 71.4%. The Enterobacteriaceae group demonstrated a 100% resistance rate to both carbapenems and third-generation cephalosporins. The average rate of MRSA (Methicillin-Resistant Staphylococcus aureus) was 67.0%.

Article Details

References

WHO bacterial priority pathogens list, 2024: Bacterial pathogens of public health importance to guide research, development and strategies to prevent and control antimicrobial resistance [Internet]. [cited 2025 June 1]. Available from: https://www.who.int/publications/i/item/9789240093461
2. Bonadonna L, Briancesco R, Coccia AM, Meloni P, Rosa GL, Moscato U. Microbial Air Quality in Healthcare Facilities. International Journal of Environmental Research and Public Health. 2021 Jan;18(12):6226.
3. Jomha MY, Yusef H, Holail H. Antimicrobial and biocide resistance of bacteria in a Lebanese tertiary care hospital. Journal of Global Antimicrobial Resistance. 2014 Dec;2(4):299–305.
4. Tille PM. Bailey and Scott’s diagnostic microbiology | Diagnostic microbiology. Fourteenth edition. Elsevier; 2017.
5. Bennett JE, Dolin R, Blaser MJ. Principles and Practices of Infectious Diseases. 8th ed. 2015.
6. Bộ Y tế. Báo cáo giám sát kháng kháng sinh tại Việt Nam năm 2020. 2023;
7. HAI Pathogens and Antimicrobial Resistance Report, 2018-2021 | NHSN | CDC [Internet]. 2025 [cited 2025 July 7]. Available from: https://www.cdc.gov/nhsn/hai-report/ narrative-commentary.html