ASSOCIATION BETWEEN MALNUTRITION AND SHORT-TERM ADVERSE OUTCOMES IN ELDERLY PATIENTS WITH ACUTE CORONARY SYNDROME

Thị Bích Hà Trịnh , Văn Trí Nguyễn, Anh Kiệt Vũ

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Abstract

Objective: To evaluate the association between malnutrition, as assessed by the Mini Nutritional Assessment–Short Form (MNA-SF), and short-term adverse outcomes, including in-hospital mortality and major adverse cardiovascular events (MACE) during hospitalization and 3 months after discharge. Method: This was a cross-sectional descriptive study with longitudinal follow-up, conducted on 375 patients aged ≥60 years admitted with acute coronary syndrome (ACS) from July 2023 to March 2024 at Thong Nhat Hospital and University Medical Center Ho Chi Minh City. Results: A total of 103 patients (28.7%) experienced adverse events either during hospitalization or within 3 months post-discharge. The incidence of cardiovascular events in malnourished patients was twice as high, and the mortality rate was three times higher compared to well-nourished patients, with statistically significant differences (p < 0.05). Multivariate Cox regression analysis identified malnutrition as an independent risk factor associated with increased risk of cardiovascular events over time. Conclusion: Malnutrition is an independent risk factor associated with an increased risk of cardiovascular events and mortality within 3 months after discharge in elderly patients with acute coronary syndrome.

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References

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