PREDICTIVE VALUE OF THE HARMS₂-AF SCORE FOR ATRIAL FIBRILLATION IN PATIENTS WITH DIABETES

Thị Thu Nguyễn, Trần Linh Phạm, Đình Phong Phan

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Abstract

Objective: To assess the HARMS₂-AF score in patients with diabetes and evaluate its value in predicting the risk of atrial fibrillation (AF) in this population. Methods: Cross-sectional descriptive study. Results: A total of 224 patients were included; mean age 71.04 ± 10.19 years, 51.34% male. Mean HbA1c was 8.5 ± 2.2%. The mean HARMS₂-AF score was 6.75 ± 2.89; most patients scored 5–9 points (51.1%). Hypertension, age, body mass index (BMI), male sex, sleep apnoea, smoking, and alcohol use were predictors of AF (all p < 0.05). Differences in HbA1c (95% CI −0.37 to 0.81, p = 0.269) and a history of COPD (95% CI 0.72–10.82, p = 0.215) were not statistically significant. The mean HARMS₂-AF score in the AF group was 7.58 ± 2.78, significantly higher than in the non-AF group (5.91 ± 2.77; p < 0.001; 95% CI 0.94–2.40). The HARMS₂-AF score showed moderate predictive performance for AF in this cohort with an AUC of 0.653. Higher HARMS₂-AF scores (≥ 5 points) were associated with increased AF risk (5–9 points: OR = 3.23; 95% CI 1.51–6.89; 10–14 points: OR = 8.71; 95% CI 3.31–22.91). Conclusion: The HARMS₂-AF score can predict the risk of atrial fibrillation among patients with diabetes mellitus; higher scores are associated with a greater likelihood of AF.

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References

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