PHÂN TÍCH THÀNH PHẦN SỎI THẬN THEO TUỔI VÀ GIỚI TÍNH

Abstract

Objective: to evaluate the association between kidney stone composition regarding age and gender. Subjects and Methods: Patients undergoing kidney stone surgery at the specialized kidney stone treatment department of Binh Dan Hospital who agreed to participate in the study were included. The prospective study described a series of cases from July 2023 to August 2024. Results: Over the course of 13 months, we collected data from 450 stone units (442 patients), of which 363 (80.67%) cases underwent percutaneous nephrolithotomy, 47 (10.44%) cases underwent retroperitoneal laparoscopic ureterolithotomy for renal pelvic or ureteral stones, 30 (6.67%) cases underwent semirigid laser ureterolithotripsy for pelvic or ureteral stones, and 10 (2.22%) cases underwent open surgery for kidney stone removal. The average age was 52.81 ±11.84 years. The male-to-female ratio was 1.45 (266/184). Calcium oxalate stones are predominant across all age groups in both genders. Whewellite stones tend to increase with age, decreasing after 70. Hydroxyapatite stones decrease with age, slightly increasing after 60. Men are generally more prone to calcium oxalate stones than women (77.06% and 45.65%, P<0.001). Specifically, whewellite stones (61.65% and 37.5%, P<0.001) and weddellite stones (15.41% and 8.15%, P=0.034) show a difference between the two genders. Women are more prone to hydroxyapatite stones than men (38.59% and 15.79%, with P<0.001), similarly with struvite stones (7.07 and 1.5%, with P =0.005). Conclusion: Calcium oxalate stones were predominant across all age groups. Males were more likely to develop calcium oxalate stones in general, whewellite and weddellite stones in particular. In contrast, females were more likely to develop hydroxyapatite and struvite stones.