NUTRITIONAL STATUS ASSESSMENT OF PATIENTS WITH ACUTE PANCREATITIS DURING THE FIRST WEEK OF HOSPITALIZATION AT HANOI MEDICAL UNIVERSITY HOSPITAL
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Abstract
Introduction: The proportion of severe acute pancreatitis is 20% with a mortality rate of 30%1,2, in which malnutrition is considered an important factor influencing prognosis and treatment outcomes. Several recommendations suggest early oral feeding in patients with mild acute pancreatitis2, and early enteral nutrition in those with moderate to severe disease3. However, nutritional assessment has not yet been standardized, with various tools such as the Subjective Global Assessment (SGA) and the Global Leadership Initiative on Malnutrition (GLIM 2018). These tools have demonstrated prognostic value, though data on patients with acute pancreatitis in Vietnam remain limited. Objective: To assess the nutritional status of patients with acute pancreatitis at Hanoi Medical University Hospital. Methods: A cross-sectional descriptive study was conducted on 75 patients with acute pancreatitis at Hanoi Medical University Hospital. Results: The mean age of the study population was 46.54 ± 13.429 years. Male patients predominated, accounting for 88%. Regarding etiologies, alcohol was the most common cause (46.7%), followed by hypertriglyceridemia (37.3%) and gallstones (5.3%). Patients with a higher risk of malnutrition (assessed using SGA and GLIM 2018) had significantly longer hospital stays, with p-values of 0.017 and 0.045 (<0.05), respectively. Early refeeding was associated with shorter hospital stays (p = 0.00 < 0.05). Conclusion: The higher the risk of malnutrition, the longer the hospital stay in patients with acute pancreatitis. The application of tools such as SGA and GLIM 2018 in clinical practice is of great importance, both in predicting the length of hospitalization and guiding early nutritional interventions to improve treatment outcomes
Article Details
Keywords
Nutrition, acute pancreatitis.
References
2. Crockett SD, Wani S, Gardner TB, et al. American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis. Gastroenterology. 2018;154(4):1096-1101. doi:10.1053/j.gastro.2018.01.032
3. Machicado JD, Wani S, Quingalahua E, et al. Practice patterns and adherence to nutrition guidelines in acute pancreatitis: An international physician survey. Pancreatology. 2021;21(3):642-648. doi:10.1016/j.pan.2021.01.001
4. Guidi M, Curvale C, Pasqua A, et al. Actualización en el manejo inicial de la pancreatitis aguda.
5. Mederos MA, Reber HA, Girgis MD. Acute Pancreatitis: A Review. JAMA. 2021;325(4):382. doi:10.1001/jama.2020.20317
6. Gliem N, Ammer-Herrmenau C, Ellenrieder V, Neesse A. Management of Severe Acute Pancreatitis: An Update. Digestion. 2021;102(4): 503-507. doi:10.1159/000506830
7. Kanthasamy KA, Akshintala VS, Singh VK. Nutritional Management of Acute Pancreatitis. Gastroenterology Clinics of North America. 2021; 50(1): 141-150. doi:10.1016/j.gtc.2020. 10.014
8. Mayerle J, Sendler M, Hegyi E, Beyer G, Lerch MM, Sahin-Tóth M. Genetics, Cell Biology, and Pathophysiology of Pancreatitis. Gastroenterology. 2019;156(7):1951-1968.e1. doi:10.1053/j.gastro.2018.11.081
9. Ocampo C, Kohan G, Leiro F, et al. Diagnóstico y tratamiento de la pancreatitis aguda en la Argentina. Resultados de un estudio prospectivo en 23 centros.
10. Khanna AK, Meher S, Prakash S, et al. Comparison of Ranson, Glasgow, MOSS, SIRS, BISAP, APACHE-II, CTSI Scores, IL-6, CRP, and Procalcitonin in Predicting Severity, Organ Failure, Pancreatic Necrosis, and Mortality in Acute Pancreatitis. HPB Surgery. 2013;2013:1-10. doi:10.1155/2013/367581